How do lungs maximize gas exchange




















Inspiratory capacity is the amount of air taken in during a deep breath, and residual volume is the amount of air left in the lungs after forceful respiration. The volume in the lung can be divided into four units: tidal volume, expiratory reserve volume, inspiratory reserve volume, and residual volume.

Tidal volume TV measures the amount of air that is inspired and expired during a normal breath. On average, this volume is around one-half liter, which is a little less than the capacity of a ounce drink bottle. The expiratory reserve volume ERV is the additional amount of air that can be exhaled after a normal exhalation. It is the reserve amount that can be exhaled beyond what is normal.

Conversely, the inspiratory reserve volume IRV is the additional amount of air that can be inhaled after a normal inhalation. The residual volume RV is the amount of air that is left after expiratory reserve volume is exhaled. The lungs are never completely empty: There is always some air left in the lungs after a maximal exhalation.

If this residual volume did not exist and the lungs emptied completely, the lung tissues would stick together and the energy necessary to re-inflate the lung could be too great to overcome. Therefore, there is always some air remaining in the lungs. Residual volume is also important for preventing large fluctuations in respiratory gases O 2 and CO 2.

The residual volume is the only lung volume that cannot be measured directly because it is impossible to completely empty the lung of air. This volume can only be calculated rather than measured. Capacities are measurements of two or more volumes.

The vital capacity VC measures the maximum amount of air that can be inhaled or exhaled during a respiratory cycle. It is the sum of the expiratory reserve volume, tidal volume, and inspiratory reserve volume. The inspiratory capacity IC is the amount of air that can be inhaled after the end of a normal expiration. It is, therefore, the sum of the tidal volume and inspiratory reserve volume.

The functional residual capacity FRC includes the expiratory reserve volume and the residual volume. The FRC measures the amount of additional air that can be exhaled after a normal exhalation. Lastly, the total lung capacity TLC is a measurement of the total amount of air that the lung can hold. It is the sum of the residual volume, expiratory reserve volume, tidal volume, and inspiratory reserve volume.

Lung volumes are measured by a technique called spirometry. An important measurement taken during spirometry is the forced expiratory volume FEV , which measures how much air can be forced out of the lung over a specific period, usually one second FEV1. In addition, the forced vital capacity FVC , which is the total amount of air that can be forcibly exhaled, is measured. Patients exhale most of the lung volume very quickly. In this instance, it is hard for the patient to get the air out of his or her lungs, and it takes a long time to reach the maximal exhalation volume.

In either case, breathing is difficult and complications arise. Of the following, which does not explain why the partial pressure of oxygen is lower in the lung than in the external air? Respiratory therapists or respiratory practitioners evaluate and treat patients with lung and cardiovascular diseases.

They work as part of a medical team to develop treatment plans for patients. Respiratory therapists may treat premature babies with underdeveloped lungs, patients with chronic conditions such as asthma, or older patients suffering from lung disease such as emphysema and chronic obstructive pulmonary disease COPD.

They may operate advanced equipment such as compressed gas delivery systems, ventilators, blood gas analyzers, and resuscitators. Because of a growing aging population, career opportunities as a respiratory therapist are expected to remain strong. The respiratory process can be better understood by examining the properties of gases.

Gases move freely, but gas particles are constantly hitting the walls of their vessel, thereby producing gas pressure. Air is a mixture of gases, primarily nitrogen N 2 ; Each gas component of that mixture exerts a pressure. The pressure for an individual gas in the mixture is the partial pressure of that gas.

Approximately 21 percent of atmospheric gas is oxygen. The functional residual capacity FRC includes the expiratory reserve volume and the residual volume. The FRC measures the amount of additional air that can be exhaled after a normal exhalation. Lastly, the total lung capacity TLC is a measurement of the total amount of air that the lung can hold.

It is the sum of the residual volume, expiratory reserve volume, tidal volume, and inspiratory reserve volume. Lung volumes are measured by a technique called spirometry. An important measurement taken during spirometry is the forced expiratory volume FEV , which measures how much air can be forced out of the lung over a specific period, usually one second FEV1.

In addition, the forced vital capacity FVC , which is the total amount of air that can be forcibly exhaled, is measured. Patients exhale most of the lung volume very quickly. In this instance, it is hard for the patient to get the air out of his or her lungs, and it takes a long time to reach the maximal exhalation volume.

In either case, breathing is difficult and complications arise. Respiratory therapists or respiratory practitioners evaluate and treat patients with lung and cardiovascular diseases. They work as part of a medical team to develop treatment plans for patients. Respiratory therapists may treat premature babies with underdeveloped lungs, patients with chronic conditions such as asthma, or older patients suffering from lung disease such as emphysema and chronic obstructive pulmonary disease COPD.

They may operate advanced equipment such as compressed gas delivery systems, ventilators, blood gas analyzers, and resuscitators. Because of a growing aging population, career opportunities as a respiratory therapist are expected to remain strong.

The respiratory process can be better understood by examining the properties of gases. Gases move freely, but gas particles are constantly hitting the walls of their vessel, thereby producing gas pressure. Air is a mixture of gases, primarily nitrogen N 2 ; Each gas component of that mixture exerts a pressure. The pressure for an individual gas in the mixture is the partial pressure of that gas. Approximately 21 percent of atmospheric gas is oxygen.

Carbon dioxide, however, is found in relatively small amounts, 0. The partial pressure for oxygen is much greater than that of carbon dioxide. The partial pressure of any gas can be calculated by:. P atm , the atmospheric pressure, is the sum of all of the partial pressures of the atmospheric gases added together,. The pressure of the atmosphere at sea level is mm Hg. Therefore, the partial pressure of oxygen is:. At high altitudes, P atm decreases but concentration does not change; the partial pressure decrease is due to the reduction in P atm.

When the air mixture reaches the lung, it has been humidified. The pressure of the water vapor in the lung does not change the pressure of the air, but it must be included in the partial pressure equation. For this calculation, the water pressure 47 mm Hg is subtracted from the atmospheric pressure:. These pressures determine the gas exchange, or the flow of gas, in the system.

Oxygen and carbon dioxide will flow according to their pressure gradient from high to low. Therefore, understanding the partial pressure of each gas will aid in understanding how gases move in the respiratory system. The ratio of carbon dioxide production to oxygen consumption is the respiratory quotient RQ. RQ varies between 0.

If just glucose were used to fuel the body, the RQ would equal one. One mole of carbon dioxide would be produced for every mole of oxygen consumed. Glucose, however, is not the only fuel for the body. Protein and fat are also used as fuels for the body.

Because of this, less carbon dioxide is produced than oxygen is consumed and the RQ is, on average, about 0. The RQ is used to calculate the partial pressure of oxygen in the alveolar spaces within the lung, the alveolar P O 2 Above, the partial pressure of oxygen in the lungs was calculated to be mm Hg. However, lungs never fully deflate with an exhalation; therefore, the inspired air mixes with this residual air and lowers the partial pressure of oxygen within the alveoli.

This means that there is a lower concentration of oxygen in the lungs than is found in the air outside the body. Knowing the RQ, the partial pressure of oxygen in the alveoli can be calculated:. With an RQ of 0. Notice that this pressure is less than the external air. In the lungs, oxygen diffuses out of the alveoli and into the capillaries surrounding the alveoli. Breathing continues during sleep and usually even when a person is unconscious The function of the respiratory system is to move two gases: oxygen and carbon dioxide.

Gas exchange takes place in the millions of alveoli in the lungs and the capillaries that envelop them. As shown below, inhaled oxygen moves from the alveoli to the blood in the capillaries, and carbon dioxide moves from the blood in the capillaries to the air in the alveoli. Three processes are essential for the transfer of oxygen from the outside air to the blood flowing through the lungs: ventilation, diffusion, and perfusion.

Diffusion is the spontaneous movement of gases, without the use of any energy or effort by the body, between the alveoli and the capillaries in the lungs. The body's circulation is an essential link between the atmosphere, which contains oxygen, and the cells of the body, which consume oxygen.

For example, the delivery of oxygen to the muscle cells throughout the body depends not only on the lungs but also on the ability of the blood to carry oxygen and on the ability of the circulation to transport blood to muscle.

In addition, a small fraction of the blood pumped from the heart Function of the Heart The heart and blood vessels constitute the cardiovascular circulatory system. Merck and Co. From developing new therapies that treat and prevent disease to helping people in need, we are committed to improving health and well-being around the world. The Manual was first published in as a service to the community.

Learn more about our commitment to Global Medical Knowledge. This site complies with the HONcode standard for trustworthy health information: verify here.



0コメント

  • 1000 / 1000