Other possible side effects may include memory problems. The occurrence of side effects is usually dependent on the dosage of the medication taken. More serious side effects are reported with high doses of benzodiazepines. Serious side effects, including respiratory depression, or shallow breathing, could indicate a medical emergency. This may not be a complete list of adverse effects that can occur. Please refer to your doctor or healthcare provider to learn more. Lorazepam and diazepam primarily interact with other drugs that affect the central nervous system CNS.
Taking these benzodiazepines with drugs like opioids, barbiturates, antipsychotics, antidepressants, and anticonvulsants can lead to increased CNS-depressant effects, such as dizziness, confusion, and drowsiness. The antigout medication probenecid can affect the metabolism of benzodiazepines and lead to increased side effects.
The use of theophylline or aminophylline can counteract the sedative effects of benzodiazepines. Tell your doctor if you take either of these drugs before starting a benzodiazepine.
Diazepam is processed by certain P enzymes whereas lorazepam is not. Some drugs can block these enzymes, which affects how well diazepam is processed in the body.
This may result in increased sedative side effects of diazepam. Drugs like ketoconazole, cimetidine, and omeprazole can interact with diazepam and lead to increased sedation. Antacids like calcium carbonate and magnesium hydroxide can decrease the absorption of diazepam in the body. This effect may alter how well diazepam works. The use of opioids with benzodiazepines should be avoided. When used together, benzodiazepines and opioids can increase the risk of respiratory depression, coma, and even death.
Patients should be monitored closely when these two classes of drugs are taken together. Lorazepam and diazepam are Schedule IV drugs. Those with a past history of alcohol or substance abuse may be at a higher risk of dependence and abuse with benzodiazepines. Dependence and abuse may increase the risk of an overdose with benzodiazepines.
Signs and symptoms of a benzodiazepine overdose include severe loss of coordination, dangerously low blood pressure hypotension , respiratory depression, and coma. Only the lowest effective dose of lorazepam or diazepam should be used. Consult a doctor or healthcare professional on other possible warnings and precautions. Lorazepam is the generic name for Ativan. It is part of a class of medications known as benzodiazepines. Lorazepam is available as an oral tablet in strengths of 0.
It can also be administered as an oral solution or injection. Lorazepam is approved to treat anxiety and insomnia caused by anxiety. It can also be used as a treatment for seizure disorders or premedication before surgery. Diazepam is also known by its brand name, Valium. It is a benzodiazepine that is FDA approved to treat anxiety, alcohol withdrawal syndrome, and muscle spasms. It can also be used for seizure disorders and sedative purposes before surgery. Diazepam is available in 2 mg, 5 mg, and 10 mg oral tablets.
It also comes as an oral solution, injection, and rectal gel. Lorazepam and diazepam are both benzodiazepines, but they are not the same. They come in different formulations and have different FDA-approved uses. Treating anxiety often involves talk therapy and antidepressant medications. Benzodiazepines are another class of medications used to help curb anxiety. Two commonly prescribed benzodiazepines are Valium and Xanax. These drugs are similar, but not exactly alike.
Both drugs are used to treat anxiety disorders. Xanax also treats panic disorder. Valium and Xanax are both brand-name versions of different generic drugs. Valium is a brand name for the drug diazepam, and Xanax is a brand name for the drug alprazolam. Both of these drugs are minor tranquilizers.
They work by helping to boost the activity of gamma-aminobutyric acid GABA. GABA is a neurotransmitter, a chemical messenger that transmits signals throughout your body. If you take Valium or Xanax, you should avoid large amounts of grapefruit or grapefruit juice.
Grapefruit blocks the enzyme CYP3A4 , which helps break down certain drugs. So having large amounts of grapefruit can increase the levels of Valium and Xanax in your body.
This can increase your risk of side effects. Xanax and Valium are in the same drug class, so they have many of the same interactions with other drugs and substances. Medications that affect your central nervous system can be dangerous when combined with benzodiazepines.
These are not all of the possible drug interactions. For a more complete list, see the interactions for diazepam and interactions for alprazolam. Always tell your doctor and pharmacist about all drugs and supplements you currently take before you start taking any new drug. Certain people should not take one or either of these drugs.
You should not take Xanax or Valium if you have acute angle-closure glaucoma also known as narrow-angle glaucoma or a history of allergic reaction to either drug. People may not be able to take certain medications alongside Valium or Xanax. A person should talk with their doctor or pharmacist and review current medications to decide what they can or cannot take.
The list below covers some of the drugs that may interact with Valium or Xanax, but there may be more. People should talk with their doctor about all possible interactions that may occur. Treatments that can interact with Valium include :. Examples of centrally acting agents include: phenothiazines, antipsychotics, anxiolytics and sedatives, hypnotics, anticonvulsants, narcotic analgesics, anesthetics, sedative antihistamines, narcotics, barbiturates, MAO inhibitors, and other antidepressants.
This is a partial list of interactions. Before starting treatment the individual should talk with their doctor or pharmacist about all medications, herbs, and supplements they are taking to ensure they are safe. Drugs and drug types that may interact with Xanax include :. The doctor may also monitor the person regularly for side effects. These medications are not suitable for everyone. A doctor will ask about existing conditions before prescribing Valium or Xanax.
Children generally cannot take Valium or Xanax. Older adults can, but they usually receive a reduced dosage. There is very little data showing the use of either Valium or Xanax in children. People should speak to their doctor if they are pregnant, are planning to become pregnant, or might become pregnant. There is no data in humans to show that either of these medications is safe or harmful during pregnancy or breastfeeding. Both drugs can cause drowsiness. A person should usually not drive or operate machinery while taking either medication.
Valium and Xanax are different, though they can treat similar issues. A doctor considers a range of factors before recommending either. Breathing exercises can help reduce anxiety. Learn how to practice deep breathing, quieting response, and three other breathing techniques here.
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